Self-learning AI provides NFL against spread, over-under, money-line picks for every 2024 Week 2 games

NFL bettors have a data point for every team in the league heading into the Week 2 NFL schedule, so it can be tempting to make bold Week 2 NFL score predictions. Cincinnati was an 8.5-point favorite coming off a loss to New England last week and has a tricky matchup against Kansas City on Sunday. The Bengals are six-point road underdogs in Week 2 NFL Odds, even though they are the last team to beat the Chiefs on the season. All four meetings between Patrick Mahomes and Joe Burrow have been decided by a field goal, so should you back the Bengals with Week 2 NFL bets?

Other NFL games today include Cowboys (-6) vs. Saints, Cardinals (-1) vs. Rams and Texans (-6.5) vs. Bears. Which Week 2 NFL spread has the highest value among NFL prospects this week? Before you make any Week 2 NFL picks, you should check out the NFL vs. Spread, Over-Under and Money Line predictions powered by SportsLine AI.

Built by SportsLine's data science team using state-of-the-art artificial intelligence and machine learning techniques, AI predictions and AI ratings are generated for each game. AI predictions quantitatively assess an opponent's defensive strength by learning statistically from each team's historical data and then assigning a numerical value out of 100 called a matchup score.

Once a prediction is formulated, an AI rating is generated using the prediction, matchup scores and market odds. For example, you might see an A-rating in an over bet if a team faces a poor defense, deviates from their prediction line, and has favorable odds.

Also, SportsLine AI is the first fully automated predictive model in SportsLine. It constantly refreshes on the latest available data and can help you spot the biggest discrepancies between lines. Last season, SportsLine's AI pickbot hit 1,674 4.5- and 5-star prop picks. Anyone who has followed it is way up.

For Week 2, AI PickBot evaluated NFL prospects and provided NFL predictions for all 16 games. You will only see AI predictions for the Week 2 NFL schedule here.

Top Week 2 NFL AI Picks

After analyzing every play in Week 2, AI Pickbot says the Jaguars are covered as three-point favorites at home against the Browns. A pair of former Clemson quarterbacks will be on the field in this matchup, but bettors may feel better about backing Trevor Lawrence over Deshaun Watson. Lawrence was strong early last season and had a steady showing against Miami, while Watson threw for just 169 yards with two interceptions in a blowout loss to Dallas.

Watson was 0-for-10 with passes that traveled at least 15 yards through the air, making his 2.2 yards per attempt the second-lowest of any quarterback in a game over the past 10 seasons (minimum 20 attempts). The Browns went 3-6 in nine road games last season and have covered the spread just once in their last five games against Jacksonville. Meanwhile, the Jaguars have covered four of their past six September games. AI PickBot won their game by an average of five points. Check out SportsLine's other Week 2 football predictions and football picks.

How to make Week 2 NFL picks

In addition, the AI ​​PickBot produced five A-rated picks for Week 2. Before making any Week 1 NFL bets of your own you should check out AI PickBot's picks. You can only watch it on Sportsline.

Who will win and cover each Week 2 NFL game and which A-rated picks should you be targeting? Visit SportsLine now to see the top NFL picks against the spread, over-under, and money line, all from the brand new SportsLine AI Pickbot that picked 1,674 top-rated picks last season.