Fantasy Football 2024 Rankings: Model's Best NFL Week 6 QB, RB, WR, TE, Kicker, Defense Picks

One Week 6 fantasy football strategy that many will follow is to target players with high over/under plays. Cowboys vs. Lions (52) and Ravens vs. Commanders (51.5) are the only games with more than 50 totals, perhaps making players from those games who are typically Week 6 fantasy football picks more attractive, such as Rico Dowdle, Jameson Williams, Mark Andrews and Jack Ertz.

Ertz has formed a strong bond with quarterback Jayden Daniels, and the Ravens have allowed both the second-most catches and yards to opposing tight ends. As the No. 2 option behind Terry McLaurin, Ertz is someone who could exceed his Week 6 fantasy football projections in the Week 6 fantasy football rankings. Before setting your fantasy football lineup, be sure to check out the Week 6 fantasy football rankings from the proven computer model at SportsLine.

When it comes to player rankings, SportsLine's model has beaten human experts in fantasy football over the past several seasons, especially when there were large differences in rankings. Over the course of a season, it can literally be the difference between winning your league or going home empty-handed.

The same model has a proven track record of providing fantasy football tips, including being ahead of the curve on players like AJ Brown, Jonathan Taylor, Derrick Henry, Christian McCaffrey, Alvin Kamara and Jahmir Gibbs. Anyone who has made their league title run relies on players like them.

Now, SportsLine has simulated the entire Week 6 NFL schedule 10,000 times and released its latest Week 6 fantasy football rankings. Head over to SportsLine to watch them now.

Top Week 6 Fantasy Football QB Rankings

Here's a look at SportsLine's top Week 6 fantasy football QB picks:

1. Lamar Jackson, Baltimore Ravens: Jackson ranks first among fantasy football quarterbacks entering Week 6, and he's coming off his best performance of the year last week against the Bengals. Jackson threw for 348 yards and four touchdowns and added 55 rushing yards in a week-winning performance.

2. Jalen Hurts, Philadelphia Eagles: Fresh off a bye week, Hurts and the Eagles drew a Browns defense that failed to impress in 2024. After leading the NFL in total defense in 2023, the Browns are 13th in yards allowed and 23rd in the NFL in scoring defense. The Commanders put up 434 yards and 34 points against Cleveland last week.

3. Jordan Love Green Bay Packers: Love averaged 8.6 yards per pass attempt in the win over the Rams and now he'll be battling a suspect Cardinals pass defense. Arizona allowed 7.1 net adjusted yards per pass attempt, which ranked 28th in the NFL this season. See more top QBs here.

Best Week 6 Fantasy Football RB Rankings

Here's a look at SportsLine's top Week 6 fantasy football RB picks:

1. Saquon Barkley, Philadelphia Eagles: Barkley's production dwindled late in his career with the Giants and an offensive line that did him no favors. However, he has been a freshman in Philadelphia, rushing for 435 yards and four touchdowns and catching 12 passes for 85 yards and a touchdown in his first four games. He should be well rested and ready to handle a heavy workload coming into the bye week.

2. Derrick Henry, Baltimore Ravens: Another returning superstar enjoying a change of scenery, Henry leads the NFL in rushing yards (572) and rushing touchdowns (6) through five weeks. While Lamar Jackson is helping hold linebackers and forcing edge defenders to focus on containment, Henry is also averaging a career-high 6.0 yards per carry.

3. Jahmir Gibbs, Detroit Lions: Gibbs is part of a backfield split with David Montgomery but has been given at least 14 touches in every game this season and has produced 361 scrimmage yards and four touchdowns in four games. Now he'll match up with a Dallas defense that ranks 24th in the NFL against the run. See more top RBs here.

Top Week 6 Fantasy Football WR Rankings

Here's a look at SportsLine's top Week 6 fantasy football WR picks:

1. CeeDee Lamb, Dallas Cowboys: After catching 135 passes for 1,749 yards and 12 touchdowns a season ago, Lamb's 2024 statline (25-378-2) may look a little pedestrian, but he's been consistently involved in the Dallas offense. He has been targeted at least seven times in every game and has at least four catches for 61 yards in every contest. Now he faces a Lions defense that ranks 27th against the pass.

2. Jayden Reed, Green Bay Packers: The fact that he's had 28 targets over five games might be a little alarming, but remember that he had Malik Willis as his quarterback in those two games. Jordan Love is back and he's healthy now and Reed made the most of his limited opportunities, adding 110 yards on 21 passes for 414 yards and two scores and another touchdown on eight carries.

3. Ja'Mar Chase, Cincinnati Bengals: After catching 10 passes for 97 yards in his first two games this season, Chase has turned it on and he's been the catalyst for the Cincinnati offense, scoring 35 points per game over the past three weeks. He has 19 catches for 396 yards and five touchdowns in that span and went 10-193-2 against the Ravens last week. Check out more top WRs here.

The best Week 6 fantasy football TE rankings

Check out SportsLine's best Week 6 fantasy football TE picks here:

1. Brock Bowers, Las Vegas Raiders: The rookie was the second-highest scoring fantasy TE in Week 5 with an 8-97-1 stat line. He was a big part of Vegas' game plan with Davante Adams out, and will be in Week 6 as well. Bowers has lived up to his high draft status and currently ranks third among TEs in fantasy points.

2. Dallas Goedert, Philadelphia Eagles: Already on the bye, Goedert ranks second among all tight ends in both catches (24) and yards (301). He leads Philly in both stats and has room to contribute even more as he has yet to find the endzone However, he has drawn multiple redzone targets, including one in his last game.

3. Zach Ferguson: Dallas Cowboys: Ferguson was injured in Week 1 and missed Week 2, but has been exceptional since returning in Week 3. Has averaged 6.3 catches for 71.3 yards over his last three games and now faces a Detroit defense that ranks 27th against the pass and allowed the tight end to combine for 56 yards and a touchdown in his last game. Check out more top TEs here.

Top Week 6 fantasy football defense rankings

Here are SportsLine's top three Week 6 fantasy football D/ST picks:

1. Texans D/ST: Houston ranks 17th in the NFL in points allowed but fourth in yards allowed. Now the Texans draw a juicy matchup against the Patriots, who averaged just 12.4 points per game in Jerrod Mayo's first season.

2. Bills D/ST: Buffalo's defense looked dominant in the first three weeks but suffered losses to the Ravens and Texans. However, it could be a fair chance to play against the jet-lagged squad that played in London last week. The Jets are 25th in the NFL in scoring.

3. Colts D/ST: The Colts have struggled on this side of the ball all season but the Titans are the NFL's most turnover-prone team. Tennessee has given up nine in four games this season, and Will Lewis has already thrown two pick-sixes this year. Check out more top D/STs here.

How to get Week 6 fantasy football rankings

Now that you know who the top three are at each position, you'll want to check out the full Week 6 fantasy football rankings from SportsLine. The model has identified a stunner in the top 10 in running backs, and knowing who it is can give you a huge edge in your league. Visit SportsLine now for Week 6 fantasy football rankings.

So who should you target in your Week 6 fantasy football rankings and which surprise RB could lead you to victory? Visit SportsLine now to get the Week 6 fantasy football rankings for every single position, from all the models that have a history of making league-winning calls, and find out.