NFL Odds, Vegas Lines, Picks, Spreads, Game Predictions: Model Backing Vikings, Chargers in Week 7, 2024

The Week 7 NFL schedule is arguably the most loaded of the year, highlighted by the Chiefs vs. 49ers Super Bowl rematch on Sunday at 4:25 pm ET. After being a 1.5-point underdog in “The Big Game” in February, Kansas City is a 1.5-point road underdog according to the latest Week 7 NFL Odds. The 49ers vs. Chiefs undercard is Vikings vs. Lions (+2.5, 50), 1 pm ET, in what could be an NFC Championship Game preview.

It's not all football fans can wait for Sunday, as other top matchups include Packers vs. Texans (+2.5, 47.5) and Giants vs. Eagles (-3, 54). As part of a Monday Night Football doubleheader, the Ravens will meet the Buccaneers, with Baltimore holding a 3.5 point advantage according to the Week 7 NFL Spread. All of the Week 7 NFL lines are listed below, and SportsLine's advanced computer model has all the NFL betting tips and NFL predictions you need to pick the best Week 7 NFL picks right now.

The model, which simulates each NFL game 10,000 times, has more than $7,000 for $100 players in top-rated NFL picks since its inception. The model enters Week 7 of the 2024 NFL season on an incredible 11-3 hot streak among this year's top-rated NFL picks. Over the long term, that's a 192-132 roll in top-rated NFL picks starting in the 2017 season and a 46-24 roll in top-rated NFL picks through Week 7 of 2022.

The model has ranked in the top 10 on NFLPickWatch over the past six years in straight-up NFL picks and has beaten more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who followed it came up with sportsbooks and betting apps.

Now, it's focused on the latest Week 7 NFL odds and NFL betting lines and locked in picks for every NFL matchup. Go here to see each pick.

Top Week 7 NFL Predictions

We can tell you one of the model's strongest Week 7 NFL picks is the Vikings (-2.5, 50) spread against the Lions. Minnesota almost won by a touchdown according to the model, as it has a pair of clear advantages in this matchup. The Vikings will be well rested, coming off a bye, while Detroit won against Dallas but defensive end Aidan Hutchinson lost arguably his best game. He led the NFL with 7.5 sacks but suffered a broken leg against the Cowboys, severely hampering Detroit's pass rush.

Even with him, the Lions were just middle-of-the-pack in pressure percentage and sacks, ranking 13th in each. He accounted for half of the team's 15 sacks, so his absence will allow Sam Darnold to find Justin Jefferson all day. Darnold is already fourth in the league in passing touchdowns and sixth in passer rating, and the SportsLine model projects he will have nearly 300 passing yards and two touchdowns on Sunday. This should enable the Vikings to cover more than 60% of the time. See other team picks here.

Another Week 7 NFL betting prediction: The Chargers (-2.5, 44) cover the road against the Cardinals on Monday Night Football. After being run-heavy in their first four games, the Chargers showed a more balanced offensive attack after their bye. Justin Herbert had 237 passing yards in the win over Denver after averaging 144.5 yards in his first four games. The running backs were still the main factor as JK Dobbins and Kimani Vidal combined for 153 scrimmage yards and two touchdowns.

As for the Cardinals, they were blown out by three touchdowns to the Packers and have a -48 point differential over Arizona's last three games. The Cards committed three turnovers in the loss, and that makes it tough to win, especially when you have the last-ranked third-down defense in the league. Kyler Murray has passed for one or fewer touchdowns in 11 of his last 14 games and won't provide enough offense to topple a resurgent Chargers attack. Los Angeles (-2.5) covers more than 60% of the time, with the model also saying the over hit is around 60% of the simulation. See other team picks here.

How to make Week 7 NFL picks

The model also made calls about who will win and cover every other game on the Week 7 NFL schedule and revealed just three coveted A-rated picks, potentially landing you a huge payday. You can get every pick for every game only at SportsLine.

So which NFL picks can you confidently pick and which three must-watch teams should you lock down now? Check out the latest NFL odds below, then head over to SportsLine to see which teams won and covered the spread, all from a proven computer model that returned more than $7,000 and find out.

Week 7 NFL Betting Odds, Lines, Spreads

Get Week 7 NFL picks on SportsLine

Thursday, October 17

Broncos at Saints (-2.5, 37)

Sunday, October 20

Patriots vs Jaguars – London (-5.5, 42.5)

Seahawks at Falcons (-3, 51.5)

Bills at Titans (-9, 41)

Bengals at Browns (+6.5, 42)

Texans at Packers (-2.5, 47.5)

Dolphins at Colts (-3.5, 44)

Lions at Vikings (-2.5, 50)

Eagles at Giants (+3, 43)

Raiders at Rams (-6.5, 43.5)

Panthers at Commander (-7.5, 51.5)

Chiefs at 49ers (-1.5, 47)

Jets at Steelers (+1.5, 38)

Monday, October 21

Ravens at Buccaneers (+3.5, 48.5)

Chargers at Cardinals (+2.5, 44)