Japan's Nikkei led declines in Asia-Pacific markets after Wall Street fell

Asia-Pacific markets traded lower on Wednesday, after Japan's Nikkei fell on Wall Street, leading losses.

Investors will look for more stimulus measures to boost China's real estate sector as the country's housing minister holds a press briefing at 10 a.m. local time on Thursday, the State Council Information Office said in a statement on Tuesday.

Housing and Urban-Rural Development Minister Ni Hong is expected to address the press conference along with officials from the central bank, finance ministry and the National Financial Regulatory Administration.

Ahead of the briefing, China's CSI 300 real estate index jumped 4.45%, while the broader benchmark CSI 300 slipped 0.3%. The Hang Seng Mainland Properties Index rose 5%, much higher than the Hang Seng Index's 0.9% rise.

Hong Kong Chief Executive John Lee pledged in his annual policy speech to strengthen the government's focus on people's livelihoods, including measures to reduce waiting times for public housing.

The city's leader has pledged to streamline procedures for companies to list in Hong Kong and attract more international companies to list on the city's stock exchange.

Traders in Asia, meanwhile, have evaluated economic data from the region. New Zealand said its consumer price index rose 2.2% year-on-year for the third quarter, in line with economists' expectations in a Reuters poll. It rose 0.6% in the quarter, slightly below the 0.7% expected.

South Korea's seasonally-adjusted unemployment rate came in at 2.5% in September, up from 2.4% in August.

of Japan Nikkei 225 Closed down 1.83% at 39,180.3, while broad-based topics ended down 1.2% at 2,690.66.

The Taiwan Weighted Index lost 1.21% to end at 23,010.98, dragged down by the technology sector.

Australia S&P/ASX 200 decreased by 0.3%.

South Korea's Kospi fell 0.6% and the small-cap Kosdaq fell 0.96%.

Overnight in the US, stocks fell amid corporate earnings season.

The Dow Jones Industrial Average lost 324.80 points, or 0.75%, to close at 42,740.42. The 30-stock average touched a new intraday record before sliding. The S&P 500 slipped 0.76% to end at 5,815.26, and the Nasdaq Composite fell 1.01% to 18,315.59.

The decline followed a strong session on Monday that sent the S&P 500 and Dow to all-time highs.

West Texas Intermediate oil futures edged higher on Wednesday, after falling more than 4% overnight, following reports that Israel told the United States it does not plan to target Iran's oil facilities with its strikes.

— CNBC's Lisa Kailai Han and Yun Lee contributed to this report.