Jets vs. Bills odds, spreads, lines, predictions: Monday Night Football picks by NFL models roll 191-131

An AFC East clash will take place on Monday Night Football as the New York Jets (2-3) host the Buffalo Bills (3-2). The winner of this game moves to first place in the division. Last Tuesday, the Jets fired head coach Robert Saleh and named Jeff Ulbricht as interim coach. Last week, the Jets lost 23-17 to the Minnesota Vikings in London. Buffalo also lost in Week 5 as the Houston Texans topped the Bills 23-20.

Kickoff from MetLife Stadium in New Jersey is set for 8:15 pm ET. Buffalo is a 1.5-point favorite in the latest Bills vs. Jets odds from SportsLine Consensus, with an over/under for total points scored of 41.5. Before locking in any Bills vs. Jets picks, check out NFL predictions and betting tips from the SportsLine projection model.

The model, which simulates each NFL game 10,000 times, has more than $7,000 for $100 players in top-rated NFL picks since its inception. The model enters Week 6 of the 2024 NFL season on an incredible 10-2 hot streak in this year's top-rated NFL picks. Over the long term, that's a 191-131 roll over top-rated NFL picks starting in the 2017 season and a 45-23 roll over top-rated NFL picks through Week 7 of 2022.

The model has ranked in the top 10 on NFLPickWatch over the past six years in straight-up NFL picks and has beaten more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has simulated Bills vs. Jets 10,000 times and just released its coveted NFL picks and Week 6 betting predictions. You can now visit Sportsline to see the model choices. Here are several NFL odds and NFL betting lines for the spread, money line and over/under for Jets vs. Bills:

• Jets vs. Bills Spread: Buffalo -1.5
• Jets vs. Bills Over/Under: 41.5 points
• Jets vs. Bills Money Line: Buffalo -120, New York +100
• BUF: Bills have scored the last goal in four of their last five away games
• NYJ: The Jets have hit 4Q totals in 11 of their last 18 games.
• Jets vs. Bills picks: See the picks on SportsLine
• Jets vs. Bills Streaming: FuboTV (Try Free)

Ken can cover the bill

Quarterback Josh Allen is a dynamic signal-caller who possesses a rocket of an arm, but will also use his legs to pick up yards. The two-time Pro Bowl selection ranks fifth in the league in touchdowns (8) and first in QBR (77.6).

Running back James Cook (questionable, foot/leg) has emerged as a key weapon on offense. Cook has strong vision and agility in open spaces. The Georgia product gives the team a weapon in the passing game. He has a team-high 309 rushing yards, 123 receiving yards and six total touchdowns. Last week, Cook had 82 rushing yards, 17 receiving yards and a score. See who to back on Sportsline.

Why can jet cover

The Jets are looking to get back into the win column and snap a two-game skid. The offense has struggled, but quarterback Aaron Rodgers is still a four-time MVP. Rodgers has a quick release and can make any throw on the field. This season, he completed 61% of his throws for 1,093 passing yards and seven passing touchdowns. Rodgers has thrown for at least 240 passing yards with two passing touchdowns in two of the last three games.

Receiver Garrett Wilson is a shifty pass-catcher with the athleticism to make defenders miss. The Ohio State product leads the team in receptions (33) and receiving yards (292) with two receiving scores. In his last outing, Wilson had 13 catches for 101 yards and a touchdown. See who to back on Sportsline.

How to build Bill vs Jet Peak

SportsLine's model leans on the total, projecting 42 combined points. The model also states that one side of the spread cache is present in more than 50% of the simulations. You can visit Sportsline to see the model options.

So who wins the Bills vs. Jets on Monday Night Football, and which side of the spread hits better 50% of the time? Head over to SportsLine now to see which side has the Bills vs. Jets back spread, from all models that returned more than $7,000 to the top-rated NFL picks, and find out.