Madonna's brother Christopher Ciccone has died at the age of 63

Madonna's brother Christopher Ciccone has died. He was 63 years old.

Christopher died of cancer in Michigan on Friday, his rep confirmed to TMZ.

The Post has reached out to reps for Madonna and Christopher for comment.

Christopher's death comes less than two weeks after his and Madonna's stepmother Joan Claire Ciccone died from cancer. One of their brothers, Anthony Ciccone, died in February 2023.

Christopher was an artist, interior decorator and designer. He served as artistic director on Madonna's Blonde Ambition World Tour in 1990 and tour director for her The Girlie Show in 1993.

He directed music videos for Dolly Parton and Tony Bennett in the 1990s.

The brother-sister duo had a falling out that Christopher chronicled in his 2008 tell-all book, “Life With My Sister Madonna,” which became a New York Times bestseller.

Christopher claimed that Madonna excluded him in a 1991 interview with The Advocate, in which he said, “My brother Christopher is gay, and he and I have always been the closest members of my family.”

He also accused Madonna's ex-husband Guy Ritchie, whom she was married to from 2000 to 2008, of being gay.

Also, Christopher said the “turning point” in his relationship with the Grammy Award winner was when he brought the camera to their mother's grave for his 1991 documentary “Truth or Dare.”

“I kept it in but I thought to myself, 'Okay, now there are no boundaries.' You know, my mother has now become a side – a bit player in her life, life story, and it hurt me. And I – my, my opinion of him changed at that moment. I never said anything about it,” he told “GMA” in 2008.

“I think, ultimately, she's a lonely person and unfortunately, it's really lonely at the top,” Kristoper added of his sister.

Christopher opened up about his relationship with the “Vogue” singer in an interview with The Evening Standard in 2012,

“As far as I am concerned, we are fine. We are in contact with each other, although I have not seen him for a long time. We are back as brothers and sisters. I don't work for him, and it's better that way,” he said.

'I couldn't be more proud of him. He is a force to be reckoned with. Does she have Barbra Streisand's voice? No,” Christopher also said of Madonna. “Can she dance like Martha Graham? Probably not. But her combination of abilities made her great, and left a huge legacy for her and through her for me. So yeah, God bless her.”

Christopher married British hairdresser Ray Thacker in 2016.

Madonna tragically lost her stepmother shortly before Christopher's death.

“Joan Claire Ciccone passed away peacefully in the early morning hours of September 24, 2024, after a brief encounter with a very aggressive cancer,” an online obituary said. “He will be terribly missed by his family and friends whose lives he enriched with his enthusiasm, joy and love.”

Joan was married to Christopher and Madonna's father Silvio for 58 years.

Their mother, also named Madonna, died in December 1963 at the age of 30.

One of Madonna's other brothers, Anthony Ciccone, died in February 2023 at the age of 66 from respiratory failure and throat cancer.

More to come…