Thursday Night Football Odds, Lines, Times, Spreads: Bills vs. Dolphins 40-27 Picks from Buffalo Experts

Week 2 of the NFL regular season begins with Thursday Night Football. The Miami Dolphins (1-0) will host the Buffalo Bills (1-0) for an AFC East duel. The Bills were able to outscore the Arizona Cardinals by 10 points in Week 1, 34-28. Likewise, the Dolphins rallied from a 14-point deficit and beat the Jacksonville Jaguars 20-17. Both teams have Super Bowl aspirations but failed to get past the divisional round last postseason. Dolphins running back Raheem Mostert (chest) is out, while De'Von Achen is officially active despite an ankle injury.

Miami, Fla. Kickoff from Hard Rock Stadium is set for 8:15 pm ET. Miami is a 2.5-point favorite on the latest Bills vs. Dolphins odds by SportsLine consensus, while the total points scored over/under is 48 after opening at 51. Before making any Dolphins vs. Bills picks, be sure to check out NFL predictions and betting tips from SportsLine expert Mike Tierney.

A veteran sportswriter whose work appears periodically in the New York Times and Los Angeles Times, Mike Tierney has covered the NFL for decades and reported from seven Super Bowls. Mike returned 154-124-9, $1,586 to $100 players in the NFL over the last two seasons. Tierney has a strong read on the bill. In fact, he is 40-27-4 (+1062) in his last 71 NFL picks in games involving Buffalo. Anyone who has followed him is way up.

Now, Tierney has locked in Bills vs. Dolphins and just released his coveted NFL picks and sports betting predictions. You can go to Sportsline now to see his picks. Here are several NFL odds and NFL betting lines on the spread, money line and over/under for Dolphins vs. Bills:

• Bills vs. Dolphins Spread: Miami -2.5
• Bills vs. Dolphins Over/Under: 48 points
• Bills vs. Dolphins money line: Dolphins -139, Bills +117
• BUF: Bills finished with 352 yards of offense in Week 1.
• MIA: Miami went 8-of-16 on third downs in Week 1
• Bills vs. Dolphins picks: See the picks on SportsLine

Ken can cover the bill

The Bills are led by quarterback Josh Allen. He is one of the top signal-callers in the league due to his ability to make plays with his hands and feet. Allen and Tua Tagovailoa have played against each other seven times and the Wyoming product has been dominant. In those matchups, Allen completed 68% of his throws for 2,035 passing yards and 19 passing touchdowns. In addition, Allen recorded 301 rushing yards and two rushing scores.

James Cook returns as another talented playmaker on the attacking end. Cook has a strong awareness of the field with speed to get around the corner. He can also be a reliable pass catcher out of the backfield. In his career, the Georgia product has 1,700 rushing yards, 657 receiving yards and nine total touchdowns. See who to back on Sportsline.

Dolphins can cover why

The Dolphins will be without running back Raheem Mostert (chest) but they do have running back Jeff Wilson Jr., who could step up for them. Wilson Jr. is a patient runner who takes his time finding open creases. In his NFL career, the North Texas product finished with 2,339 rushing yards and 18 touchdowns. He also grabbed 71 receptions for 566 yards and five scores.

The biggest weapon in Miami's offense is wide receiver Tyreek Hill. The eight-time Pro Bowl selection is hard to pin down because of his game-breaking speed and sure hands to reel the ball in. Since joining Miami, he has finished with 1,700 yards in back-to-back seasons. In 2023, the 30-year-old posted 119 receptions with a career-high 1,799 receiving yards and 13 touchdowns. See who to back on Sportsline.

How to pick Bills vs. Dolphins

Tierney leans under Mote. He also found a critical X-factor that he says hits hard on the side of the spread. Find out what it is on SportsLine.

So who wins on Thursday Night Football, Dolphins vs. Bills, and what important X-factor hits one side the hardest? Head over to SportsLine now to see which side has the Dolphins vs. Bills back spread, 40-27 picks from all the experts involving Buffalo, and find out.