Lady Gaga Diagnoses Her Pop Music Return With New 'Disease' Single: Stream It Now

Seven years after offering a “cure,” Lady Gaga is finally getting a “disease” diagnosis.

After some sly teasing via a Spotify playlist and a pair of custom websites, Gaga finally confirmed the single's release date via Instagram on Monday (October 21). In the post, the Grammy and Oscar winner shared the single's cover art, in which she poses face-down on the hood of a white car with the song's title written upside down in street paint. The next day (October 22), he shared a short teaser of what appears to be the song's official music video, which is soundtracked by Piano Keys. “I could play doctor/ I could cure your diseases/ If you were a sinner/ I could make you believe,” he crooned on the lead single for his eighth solo studio album.

Gaga has been very musically active in 2024. In August, he teamed up with Bruno Mars for the song “Die With a Smile” which peaked at number 3 on the Billboard Hot 100 and spent eight weeks atop the Billboard Global 200. The following month, Pop Icon launched HarlequinA companion soundtrack album for Joker: Folie à Deuxwhere she stars as Harley Quinn alongside Oscar winner Joaquin Phoenix. Features Gaga-fied versions of several jazz and musical theater standards, including “That's Entertainment” and “Oh, When the Saints” Harlequin Jazz debuted atop the album, becoming Gaga's third No. 1 entry on the chart. Harlequin There's also an original cut: the Bloodpop-produced “Happy Mistake.”

It's been four years since Gaga debuted at the top of the Billboard 200 color scienceHer last solo studio album, which featured the Grammy-winning Billboard Hot 100 chart-topper “Rain on Me” (with Ariana Grande). Mother Monster boasts six Billboard 200 No. 1 albums and five Hot 100 No. 1 singles, including 2009's “Poker Face” (one week), 2011's “Born This Way” (six weeks) and 2018's Bradley Cooper – Assistant “Shallow” (one week).

Stream “Disease” now.