49ers beat Seahawks on Thursday Night Football as receiver sets historic mark | CNN

The San Francisco 49ers enter Thursday Night Football against division rival Seattle Seahawks after a stunning home loss to the Arizona Cardinals last time out.

And though there were some nervy moments, the 49ers were able to get back on track with their 36-24 win at Lumen Field.

After blowing a 13-point lead against the Cardinals in Week 5, it looked like the 49ers were well on their way to banishing those monsters as they took a 16-3 halftime lead before going on a 23-3 run.

But Seattle's Laviska Chenault's 97-yard kickoff return touchdown cut into that lead on the next play, while Kenneth Walker's one-yard touchdown run made it a six-point game with just over half left in the fourth quarter.

Unlike against Arizona, though, the 49ers didn't buckle under the pressure. A nine-yard pass from Brock Purdy to George Kittle and a six-yard run from Kyle Juszczyk meant San Francisco remained in front of whatever comeback Seattle tried to mount.

After disappointing losses to the Cardinals and Los Angeles Rams in recent weeks, head coach Kyle Shanahan said he felt “sick” about the results.

But after Thursday's win, he said he was more impressed with how his team bounced back against the Seahawks.

“We talked about these two losses as a reminder of how the NFL works,” Shanahan told reporters. “I think we're a bit spoiled in the way of human nature, sometimes feeling too relaxed and you can never feel too relaxed.

“I thought we played very well in the second half, but that doesn't mean it's easy to win. That's kind of how it works. We played well. They played well. They came back and made some plays, which made it tougher, and I'm glad our guys were able to fight through it, realizing that games are never really over where you can sit back and chill in the fourth quarter. You have to go from start to finish, and we experienced that today.”

Purdy led the offense with a clean performance, completing 18 of his 28 throws for 255 yards and three touchdowns.

The 49ers' running game suffered a setback midway through the second quarter when Jordan Mason — who was already standing in for Christian McCaffrey — left the game with a shoulder injury. Mason rushed nine times for 73 yards in that span.

However, San Francisco didn't miss a beat on the ground as rookie Isaac Guerredo carried the ball 10 times for 99 yards.

The defense, which was missing some key starters, did a great job of Seattle's offense, holding it to just 52 rushing yards and intercepting quarterback Geno Smith twice, including on the first drive of the game.

It was a special game for 49ers wide receiver DeBo Samuel, who made NFL history during Thursday's encounter.

The dual-threat offensive weapon, known for his receiving and rushing ability, scored on a 76-yard touchdown catch midway through the second quarter. In doing so, he became the first wide receiver in NFL history with 20 touchdown receptions and 20 touchdown runs.

And then, Samuel talked about the importance of Thursday's win as San Francisco improved to 3-3.

“It was definitely a must-win, but (I) had a little different approach to the must-win,” Samuels, who finished the game with 102 receiving yards on three receptions along with 15 rushing yards, told reporters.

“You have to win, if you lose, you're done. So, at the end of the day, we definitely consider it a win to get back on track.”